- Stage 2A Colon Cancer
- Stage 2B Colon Cancer
- Stage 2C Colon Cancer
Overview
Stage 2A Colon Cancer is when the colon cancer is invading the deepest layer of your colon called the serosa, shown here as a thin dark pink band running across the middle of the image on the left.
What Tests Will I Need and Why?
Blood and Imaging tests are done to understand your general health, confirm your diagnosis and determine your cancer stage.
A test, called a Colonoscopy, is usually the first step to see if there is a tumor inside of your colon and if needed, to take tissue samples for analysis. This test, inserts a thin tube with a camera into your anus to see the inside of your colon.
Tissue analysis is also typically done through a biopsy to identify a biomarker called Microsatellite Instability High (MSI-H) or Mismatch Repair Deficiency (MMRd). Identifying a biomarker in your body is critical to finding the best treatment option for you. About 15-25% of all Colorectal Cancers have MSI-H.
Re-read this summary as needed and then tap, “Compare My Treatment Options Now“. Our unique Comparison Page will help you understand your FDA-approved treatment options including, who can help you pay for your treatment, where and how each is given and what side-effects you may experience.

National Institute of Health/ treatment-colon
Overview
Stage 2B Colon Cancer is when the cancer has spread to the tissue that covers most of the organs in your abdomen called the visceral peritoneum, shown here in the middle picture.
What Tests Will I Need and Why?
Blood and Imaging tests are done to understand your general health, confirm your diagnosis and determine your cancer stage.
A test, called a Colonoscopy, is usually the first step to see if there is a tumor inside of your colon and if needed, to take tissue samples for analysis. This test, inserts a thin tube with a camera into your anus to see the inside of your colon.
Tissue analysis is also typically done through a biopsy to identify a biomarker called Microsatellite Instability High (MSI-H) or Mismatch Repair Deficiency (MMRd), which is critical to finding the best treatment option for you. About 15-25% of all Colorectal Cancers have MSI-H.
Re-read this summary as needed and then tap, “Compare My Treatment Options Now“. Our unique Comparison Page will help you understand your FDA-approved treatment options including, who can help you pay for your treatment, where and how each is given and what side-effects you may experience.

National Institute of Health/ treatment-colon
Overview
Stage 2C Colon Cancer is when the Colon Cancer has spread outside of the colon to nearby organs such as your kidney, prostate, cervix, or vagina, indicated here by the blue arrow leaving the colon in the image on the right.
What Tests Will I Need and Why?
Blood and Imaging tests are done to understand your general health, confirm your diagnosis and determine your cancer stage.
A test, called a Colonoscopy, is usually the first step to see if there is a tumor inside of your colon and if needed, to take tissue samples for analysis. This test, inserts a thin tube with a camera into your anus to see the inside of your colon.
Tissue analysis is also typically done through a biopsy to identify a biomarker called Microsatellite Instability High (MSI-H) or Mismatch Repair Deficiency (MMRd), which is critical to finding the best treatment option for you. About 15-25% of all Colorectal Cancers have MSI-H.
Re-read this summary as needed and then tap, “Compare My Treatment Options Now“. Our unique Comparison Page will help you understand your FDA-approved treatment options including, who can help you pay for your treatment, where and how each is given and what side-effects you may experience.

National Institute of Health/ treatment-colon
Recommended Colon Cancer Videos

Colorectal Cancer Overview

The 4 Stages of Colon Cancer in 3D
Colorectal Cancer Prevention: Dr. Mark Pochapin on Colonoscopy & Polypectomy

How Cancer Spreads
Metastatic = Advanced

Diagnosing Your Cancer
How Does a PET Scan Work?

Diagnosing Your Cancer
How Does a CT Scan Work?

Get Up & Get Moving
From Your Friends @ the Oncology Nursing Society
Commonly Searched Questions
Stage 2 Colon Cancer Definition
Source: Cancer.org
Stage 2 Colon Cancer Survival Rate
Source: Cancer.gov
Stage 2 Colon Cancer Treatment
Source: Cancer.org
Stage 2 Colon Cancer Symptoms
- constipation
- changes in stool color
- changes in stool shape, such as narrowed stool
- blood in the stool
- bleeding from the rectum
- excessive gas
- abdominal cramps
Source: Cancer.org
Stage 2 Colon Cancer Recurrence Rate
- Overall Recurrence Rate: The recurrence rate for Stage 2 colon cancer is lower compared to more advanced stages. The 5-year survival rate for Stage 2 colon cancer is around 70-85%, indicating a relatively favorable prognosis, though exact recurrence rates can differ.
- Risk Factors Influencing Recurrence: High-risk features such as poor differentiation of the tumor, invasion into the outer layers of the colon, or involvement of nearby lymph nodes can increase the risk of recurrence.
Source: Cancer.org
Stage 2 Colon Cancer Prevention
- Regular Screening: Begin screening for colon cancer at age 45, or earlier if at higher risk, using methods such as colonoscopy to detect and remove precancerous polyps before they develop into cancer.
- Healthy Diet: Eat a diet high in fruits, vegetables, and whole grains, and low in red and processed meats.
- Regular Exercise: Engage in regular physical activity.
- Healthy Weight: Maintain a healthy body weight.
- Limit Alcohol: Drink alcohol in moderation.
- Avoid Tobacco: Do not smoke.
- Manage Chronic Conditions: Address conditions like inflammatory bowel disease, which increase colon cancer risk.
Source: Cancer.org